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Validation of COPD Population Screener Questionnaire in Chinese Population: A National Multicenter Study
Zijie Zhan1,2,3,4, Yiming Ma1,2,3,4, Yahong Chen5
1Department of Respiratory Medicine, Second Xiangya Hospital, Central South University, Changsha, China.
Introduction:
Chronic obstructive pulmonary disease (COPD) is highly prevalent and underdiagnosed worldwide. The validity and reliability of COPD Population Screening (COPD-PS) questionnaire are not properly known in a large-sample Chinese population.
Methods:
This is a national multicenter prospective study that enrolled 1,824 outpatients from 12 hospital sites in China. Scores of the Chinese version of COPD-PS questionnaire, demographic data, and clinical information were collected. The validity and the test-retest reliability were evaluated.
Results:
1,824 participants were involved in this study, and 404 (22.1%) were diagnosed with COPD. The overall area under the curve (AUC) of the receiver operating characteristic (ROC) for COPD-PS questionnaire was 0.761 (95% CI: 0.734-0.787). A cut-off point of 4 was recommended, corresponding to a sensitivity of 74.50% and a specificity of 64.37%. The COPD-PS questionnaire showed an overall Pearson's correlation of 0.88.
Conclusions:
The COPD-PS questionnaire can be used in screening COPD patients from the general Chinese population with respiratory symptoms.
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