THE RELATION OF THYROID DISTURBANCE AND ISCHEMIC HEART DISEASE IN IRAQI PATIENTS

Area of Science:

• Endocrinology
• Cardiology
• Metabolic Disorders

Background:

• Ischemic heart disease (IHD) is a significant global health concern.
• Thyroid dysfunction is increasingly recognized as a potential comorbidity affecting cardiovascular health.
• Understanding the interplay between thyroid function and IHD is crucial for comprehensive patient management.

Purpose of the Study:

• To investigate thyroid function parameters in patients with ischemic heart disease (IHD) in Baghdad.
• To compare thyroid hormone levels (T3, T4, TSH) and HbA1c between IHD patients and healthy controls.
• To explore correlations between thyroid dysfunction, hypertension, diabetes, and IHD.

Main Methods:

• A case-control study involving 60 Iraqi IHD patients and 30 healthy controls.
• Blood samples analyzed for thyroid hormones (T3, T4, TSH) and glycated hemoglobin (HbA1c) after fasting.
• Demographic data including age, sex, BMI, hypertension, and diabetes status were collected and analyzed.

Main Results:

• IHD patients exhibited significantly higher triiodothyronine (T3) and thyroxine (T4) levels compared to controls.
• No significant difference in thyroid-stimulating hormone (TSH) levels was observed between groups.
• Elevated HbA1c levels were noted in hypothyroid patients, and hyperthyroidism was more prevalent in hypertensive individuals, while hypothyroidism was more common in diabetics.

Conclusions:

• The study suggests potential alterations in thyroid hormone levels associated with ischemic heart disease.
• Findings indicate a possible link between thyroid dysfunction and the prevalence of hypertension and diabetes in IHD patients.
• Further research is warranted to elucidate the clinical implications and underlying mechanisms of thyroid dysfunction in IHD.