Nanoparticles as Drug Delivery Carrier-synthesis, Functionalization and Application

Area of Science:

• Chemistry
• Materials Science
• Nanotechnology
• Pharmacology

Background:

• Advancements in chemistry enable precise tailoring of materials at the nanoscopic level.
• Nanomaterials are increasingly utilized as advanced drug delivery systems.
• Traditional drug delivery methods often face challenges with stability and systemic toxicity.

Purpose of the Study:

• To review the diverse types of nanomaterials employed as drug carriers.
• To discuss the synthesis and surface modification techniques for nano-drug carriers.
• To explore the applications and future prospects of nanomaterials in biomedical drug delivery.

Main Methods:

• Literature review of recent advancements in nanomaterial-based drug delivery.
• Categorization of nanomaterials into metal-based, organic, inorganic, and polymer types.
• Analysis of nanoparticle synthesis, surface coating, and drug encapsulation strategies.

Main Results:

• Nanomaterials enhance drug stability and therapeutic index while reducing side effects.
• Surface coating with surfactants allows for controlled drug release and tailored solubility.
• Various nanomaterial types demonstrate significant potential for targeted drug delivery.

Conclusions:

• Nanomaterials represent a promising frontier for developing safer and more effective drug delivery systems.
• Further research into synthesis, functionalization, and clinical translation is crucial.
• The tailored properties of nanomaterials offer significant advantages for future biomedical applications.