Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.8K
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

1.8K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
1.8K
Skin Cancer01:30

Skin Cancer

4.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.1K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Papillary Dermis01:11

Papillary Dermis

2.8K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
2.8K
Hypersensitivities01:30

Hypersensitivities

615
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
615

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Utility of p16, p21, and PRAME Immunohistochemistry in Melanocytic Lesions.

The American Journal of dermatopathology·2026
Same author

Artificial Intelligence-Based Risk Prediction Models for Complications After Tongue Cancer Surgery.

JAMA otolaryngology-- head & neck surgery·2026
Same author

Inducible lipid storage and steatosis in the human choroid plexus associated with age and adiposity.

bioRxiv : the preprint server for biology·2026
Same author

Renal function outcomes following endoscopic management of upper tract urothelial carcinoma.

World journal of urology·2026
Same author

Patterns of adjuvant intracavitary instillation and recurrence after endoscopic management of upper tract urothelial carcinoma.

World journal of urology·2026
Same author

Association Between Hospital Participation in the Global Budget Revenue Model and Surgical Outcomes Among Traditional Medicare Beneficiaries Undergoing Cancer Surgery.

Annals of surgery·2026

Related Experiment Video

Updated: Jun 26, 2025

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

9.7K

Clinical Presentation of Atopic Dermatitis.

Christine Ahn1, William Huang2

  • 1Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC, USA. cahn@wakehealth.edu.

Advances in Experimental Medicine and Biology
|May 9, 2024
PubMed
Summary

Atopic dermatitis, or eczema, is a chronic skin condition causing intense itching and rashes. Its diagnosis can be complex due to varied presentations across different individuals.

Keywords:
Aatopic dermatitisAdult ADAtopic triadAtopyChildhood ADDiagnostic criteriaImmunoglobulin E (IgE)Infantile ADPostinflammatory pigmentationPrevalence

More Related Videos

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.2K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

58

Related Experiment Videos

Last Updated: Jun 26, 2025

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

9.7K
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.2K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

58

Area of Science:

  • Dermatology
  • Immunology
  • Clinical Medicine

Background:

  • Atopic dermatitis (eczema) is a chronic inflammatory skin disease.
  • Characterized by pruritus and distinct clinical findings.
  • Affects all age groups, from infancy to adulthood.

Purpose of the Study:

  • To review classical and less common manifestations of atopic dermatitis.
  • To highlight diagnostic challenges in atopic dermatitis.
  • To discuss variability in clinical presentation.

Main Methods:

  • Literature review of atopic dermatitis.
  • Analysis of clinical presentations.
  • Synthesis of diagnostic criteria.

Main Results:

  • Atopic dermatitis presents with significant pruritus and characteristic skin findings.
  • Clinical manifestations vary widely based on age, skin type, ethnicity, and comorbidities.
  • Diagnosis can be challenging due to diverse presentations.

Conclusions:

  • Understanding the spectrum of atopic dermatitis is crucial for accurate diagnosis.
  • Recognizing both common and uncommon signs aids in effective patient management.
  • Variability in presentation necessitates a comprehensive diagnostic approach.