[AL Amyloidosis]
1Department of Neurology, Graduate School of Medical Sciences, Kumamoto University.
Brain and Nerve = Shinkei Kenkyu No Shinpo
|May 14, 2024
Abstract:
AL amyloidosis, derived from amyloidogenic immunoglobulin light chains, is a common type of systemic amyloidosis. Peripheral neuropathy has been identified in 10%-40% of patients with systemic AL amyloidosis. Definitive diagnosis requires tissue biopsies, including skin, fat, and gastrointestinal samples, as well as amyloid typing. Disease-modifying therapies have been shown to improve patient survival and prevent progressive organ dysfunction.
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