INVESTIGATION OF IRON DEFICIENCY IN POSTMENOPAUSAL WOMEN BASED ON LABORATORY TESTING: A UNI-CENTRE STUDY

Area of Science:

• Hematology
• Endocrinology
• Gerontology

Background:

• Postmenopausal women experience hormonal changes leading to potential health issues.
• Hematological deficits, including anemia, are a recognized consequence of estrogen deficiency.

Purpose of the Study:

• To investigate the detection of anemia in postmenopausal women.
• To identify specific hematological parameter alterations in postmenopausal women using accessible laboratory tools.

Main Methods:

• Retrospective analysis of patient data from 2014-2022.
• Comparison of hematological parameters in postmenopausal women against standard reference ranges.
• Stratification of participants into age groups (45-55, 56-65, 66-80 years) for detailed analysis.

Main Results:

• Postmenopausal women exhibited reduced hemoglobin, packed cell volume, mean corpuscular volume, and mean corpuscular hemoglobin.
• Elevated red cell distribution width and serum iron levels were observed.
• No significant changes were noted in red blood cell count, MCHC, iron binding capacity, transferrin saturation, serum ferritin, WBC count, or platelets.
• Older age groups showed a greater number of altered hematological parameters.

Conclusions:

• Postmenopausal hormone alterations significantly impact hematological parameters.
• Routine laboratory tests are effective tools for assessing blood parameter changes in postmenopausal women.
• Age is a contributing factor to the severity of hematological alterations in this demographic.