Open-source spring-driven syringe pump with 3D-printed components for microfluidic applications

Area of Science:

• Engineering
• Biomedical Engineering
• Materials Science

Background:

• Microfluidic devices require precise fluid flow, crucial for point-of-care testing (POCT).
• Existing open-source pumps often rely on electricity, limiting their use in resource-limited settings.
• A portable, inexpensive, and electricity-free pumping solution is needed for widespread microfluidic adoption.

Purpose of the Study:

• To develop and introduce a novel spring-driven, 3D-printed syringe pump.
• To provide an electricity-free alternative for operating microfluidic devices.
• To enable microfluidic applications in low-resource environments.

Main Methods:

• Fabrication of all pump components using 3D printing technology.
• Utilizing the torque of a manually wound flat spiral spring to drive the syringe plunger.
• Implementing interchangeable gear combinations to adjust flow rates based on syringe size and desired velocity.

Main Results:

• Successful development of a functional, electricity-free syringe pump.
• Achieved variable flow rates through different syringe sizes and gear ratios.
• Demonstrated a low fabrication cost of $25-30 per unit.

Conclusions:

• The proposed syringe pump offers a viable, low-cost solution for microfluidic applications in resource-limited settings.
• This innovation can significantly promote the use of microfluidics in remote and underserved areas.
• The device's user-friendly design and ease of assembly further enhance its potential impact.