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Updated: Jun 12, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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3,3-Difluorooxetane-A Versatile Functional Group for Bioisosteric Replacements in Drug Discovery

Oleksandr S Liashuk1,2, Anastasiya Fedinchyk1,2, Kostiantyn P Melnykov1,2

  • 1Enamine Ltd., Winston Churchill Street 78, 02094, Kyїv, Ukraine.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|September 20, 2024
PubMed

Keywords:
BioisosteresBuilding blocksFluorineFunctional groupsOxetane

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