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Updated: Jun 6, 2025

Protocols of 3D Bioprinting of Gelatin Methacryloyl Hydrogel Based Bioinks
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Protocols of 3D Bioprinting of Gelatin Methacryloyl Hydrogel Based Bioinks

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Hydrogel Fibers-Based Biointerfacing.

Xingmei Chen1, Yinghui Feng1, Pei Zhang1

  • 1Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen, 518055, China.

Advanced Materials (Deerfield Beach, Fla.)
|November 22, 2024
PubMed
Summary
This summary is machine-generated.

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Hydrogel fibers offer a promising solution for seamless biointerfacing due to their tissue-like properties. This review explores their manufacturing, functionality, and biomedical applications for advanced health monitoring and treatment.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Medical Device Technology

Background:

  • Traditional fiber devices lack compatibility with biological systems due to their rigid, non-living nature.
  • Hydrogel fibers mimic biological tissues in mechanical, chemical, and biological aspects, offering superior biointerfacing capabilities.
  • The unique 1D structure of fibers provides advantages like high length-to-diameter ratio, miniaturization, light-weight, and flexibility.

Purpose of the Study:

  • To provide a comprehensive overview of recent advancements in hydrogel fibers for biointerfacing technology.
  • To summarize manufacturing strategies and functional designs of hydrogel fibers, focusing on optical, conductive, and responsive properties.
  • To examine the diverse biomedical applications enabled by these advanced hydrogel fibers.
Keywords:
bioelectronicsbiointefacingbiomedicalhydrogel fibersmanufacturing

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Last Updated: Jun 6, 2025

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Main Methods:

  • Review of recent scientific literature on hydrogel fiber fabrication and application.
  • Analysis of manufacturing strategies, including functional design for optical, electronic, and responsive properties.
  • Evaluation of hydrogel fibers' performance in various biomedical contexts.

Main Results:

  • Hydrogel fibers exhibit tunable optical and electron conductive performance.
  • These fibers demonstrate responsiveness to external triggers such as thermal, magnetic, and ultrasonic fields.
  • Successful application of hydrogel fibers in health monitoring, disease treatment, and minimally invasive surgeries is highlighted.

Conclusions:

  • Hydrogel fibers represent a next-generation biointerfacing technology with significant potential.
  • Future directions include addressing biosafety, long-term reliability, sterilization, and multi-modal integration.
  • Further development is crucial for intelligent therapeutic systems and widespread clinical implementation.