Cognitive Orientation to Daily Occupational Performance (CO-OP) in Parkinson's: Randomized Trial Findings.

Area of Science:

• Neurorehabilitation
• Occupational Therapy
• Clinical Trials

Background:

• Parkinson's disease (PwPD) leads to progressive disability affecting motor and non-motor functions.
• Comprehensive rehabilitation is crucial for maximizing daily functioning in PwPD.
• Cognitive Orientation to daily Occupational Performance (CO-OP) is a targeted approach with proven efficacy in similar conditions.

Purpose of the Study:

• To assess the feasibility and potential benefits of CO-OP for individuals with Parkinson's disease.
• A randomized controlled trial (RCT) was designed to explore CO-OP's applicability in PwPD.
• Investigate CO-OP's impact on goal attainment, functional status, and quality of life.

Main Methods:

• A parallel-group, assessor-masked RCT involved 20 PwPD.
• Participants were randomized to either the CO-OP intervention (20 sessions over 10 weeks) or a waitlist control (WLC).
• Outcome measures included goal attainment, functional and cognitive status, quality of life, self-efficacy, transfer, and maintenance.

Main Results:

• High ratings for effort and enjoyment, along with strong homework completion (91%) and protocol adherence (82%), indicate CO-OP's feasibility.
• CO-OP significantly outperformed the WLC in Canadian Occupational Performance Measure (COPM) performance and satisfaction, and the Performance Quality Rating Scale (PQRS).
• No significant difference was found between groups on the Goal Attainment Scale (GAS).

Conclusions:

• CO-OP is implementable, feasible, and shows potential benefits for people with Parkinson's disease.
• The findings address a significant gap in Parkinson's disease management strategies.
• Further research is recommended to definitively establish the efficacy of CO-OP for PwPD.