Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Force Microscopy01:08

Atomic Force Microscopy

3.3K
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The ITM2B-associated retinal dystrophy mutation modifies BRI23 peptide interactions in the human retina.

Scientific reports·2026
Same author

<i>In vivo</i> characterization of a retinal cellular biomarker of inflammation in multiple sclerosis.

Brain communications·2026
Same author

Imaging of Tissue and Cell Dynamics: introduction to the feature issue.

Biomedical optics express·2026
Same author

Influence of retinal eccentricity, color blindness, and age on optoretinography measured with AOSLO.

Biomedical optics express·2025
Same author

Wide-field cellular-resolution retinal imaging using deformable mirror-based sensorless adaptive optics time-domain full-field OCT.

Biomedical optics express·2025
Same author

Rapid spectral shaping for time domain and swept source full field OCT.

Biomedical optics express·2025
Same journal

Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

Optics letters·2026
Same journal

E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

Optics letters·2026
Same journal

Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

Optics letters·2026
Same journal

Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

Optics letters·2026
Same journal

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026
Same journal

Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

Optics letters·2026
See all related articles

Related Experiment Video

Updated: May 16, 2025

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

18.6K

Rolling-phase dynamic full-field OCT.

Tual Monfort, Kate Grieve, Olivier Thouvenin

    Optics Letters
    |April 1, 2025
    PubMed
    Summary
    This summary is machine-generated.

    A new rolling-phase dynamic full-field optical coherence tomography (RP-DFFOCT) method significantly improves image quality by reducing artifacts. This label-free microscopy technique enhances visualization of subcellular structures and cellular activity.

    More Related Videos

    Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
    00:09

    Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales

    Published on: August 21, 2019

    6.8K
    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
    12:22

    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

    Published on: August 4, 2018

    8.4K

    Related Experiment Videos

    Last Updated: May 16, 2025

    Doppler Optical Coherence Tomography of Retinal Circulation
    10:46

    Doppler Optical Coherence Tomography of Retinal Circulation

    Published on: September 18, 2012

    18.6K
    Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
    00:09

    Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales

    Published on: August 21, 2019

    6.8K
    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
    12:22

    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

    Published on: August 4, 2018

    8.4K

    Area of Science:

    • Biomedical Optics
    • Microscopy
    • Cellular Imaging

    Background:

    • Dynamic full-field optical coherence tomography (DFFOCT) offers label-free imaging with high speed and sectioning.
    • Image quality in DFFOCT is often compromised by phase noise and fringe artifacts.

    Purpose of the Study:

    • To introduce a novel implementation of DFFOCT, termed rolling-phase DFFOCT (RP-DFFOCT).
    • To demonstrate RP-DFFOCT's capability to overcome common DFFOCT image degradation issues.
    • To show simultaneous extraction of static and dynamic contrast.

    Main Methods:

    • Implementation of RP-DFFOCT with a slowly scanned reference arm exceeding 2π.
    • Mathematical and experimental validation of the RP-DFFOCT approach.
    • Application of RP-DFFOCT to a macaque retinal explant.

    Main Results:

    • RP-DFFOCT significantly reduces phase noise and fringe artifacts, leading to superior image quality.
    • The method successfully extracts both static and dynamic contrast information.
    • Enhanced resolution of subcellular structures, including intranuclear activity, was observed.

    Conclusions:

    • RP-DFFOCT represents a significant advancement in label-free microscopy.
    • The technique provides improved image quality and richer contrast information compared to conventional DFFOCT.
    • RP-DFFOCT holds promise for detailed cellular and subcellular imaging applications.