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2D:4D ratio as a predictor for malocclusion among Saudi children
Ahmed Ali Alfawzan1, Mohammed Ali Habibullah1, Nada Mohammed Aloufi1
1Department of Orthodontic and Pediatric Dentistry, College of Dentistry, Qassim University, Kingdom of Saudi Arabia.
Bioinformation
|April 21, 2025
Summary
The 2D:4D ratio, indicating prenatal hormone exposure, showed no significant link to malocclusion types in Saudi male students. This suggests the ratio is not a reliable predictor for malocclusion, highlighting complex contributing factors.
Area of Science:
- Anthropology
- Dentistry
- Endocrinology
Background:
- The 2D:4D digit ratio is a marker of prenatal androgen exposure.
- This ratio may influence skeletal and dental development.
- Malocclusion, a deviation in tooth alignment, has multifactorial causes.
Purpose of the Study:
- To investigate the correlation between the 2D:4D digit ratio and malocclusion types.
- To assess the potential of the 2D:4D ratio as a predictor of malocclusion in adolescents.
Main Methods:
- A study involving 410 male students aged 12-15 years from Alrass City, Saudi Arabia.
- Measurement of the 2D:4D ratio (index to ring finger length).
- Classification of malocclusion using Angle's classification system.
- Statistical analysis using Chi-Square tests.
Main Results:
- No statistically significant association was found between the 2D:4D digit ratio and malocclusion types (p=0.904).
- The findings indicate the 2D:4D ratio is not a reliable predictor for malocclusion in this cohort.
Conclusions:
- The 2D:4D ratio does not appear to be a significant factor in the development of malocclusion.
- Further research is needed to understand the complex interplay of hormonal, genetic, and environmental factors in craniofacial growth and malocclusion.
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