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Metal-organic framework-based nanozymes: types, activity regulation and analytical applications
Mingyue Xie1, Shidun Chen2, Ke Chen1
1Henan Chemical Industry Research Institute Co., Ltd, No. 37 Jianshe East Rd, Zhengzhou 450052, China.
The Analyst
|June 30, 2025
Summary
Metal-organic frameworks (MOFs) are versatile nanomaterials acting as enzyme mimics (nanozymes). This review details strategies to enhance MOF nanozyme activity for improved catalytic performance and analytical applications.
Area of Science:
- Materials Science
- Catalysis
- Nanotechnology
Background:
- Nanomaterial-based enzyme mimics (nanozymes) offer advantages over natural enzymes due to superior stability.
- Metal-organic frameworks (MOFs) are promising nanozyme candidates owing to their tunable structures and diverse components.
Purpose of the Study:
- To review strategies for enhancing the enzyme-mimicking activity of MOF-based nanozymes.
- To discuss the catalytic mechanisms, analytical applications, and future prospects of MOF nanozymes.
Main Methods:
- Literature review focusing on MOF nanozyme research.
- Analysis of strategies for activity enhancement.
- Summarization of catalytic mechanisms and applications.
Main Results:
- MOFs exhibit significant potential as nanozymes due to their structural versatility.
- Various strategies effectively regulate and enhance the catalytic activity of MOF nanozymes.
- MOF nanozymes have demonstrated broad applicability in analytical sensing.
Conclusions:
- MOF-based nanozymes represent a rapidly advancing field with significant potential.
- Further research into activity enhancement strategies is crucial for high-performance applications.
- Addressing current challenges will drive the future development of MOF nanozymes.
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