Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

1.1K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
1.1K
Structure of Cardiac Muscles01:13

Structure of Cardiac Muscles

14.1K
Cardiac muscle, or myocardium, is a specialized type of muscle found exclusively in the heart. Its unique structural and functional characteristics enable the heart to perform its vital role of pumping blood throughout the body continuously and rhythmically. The cardiac muscle cells, or cardiomyocytes, possess an endomysium and perimysium but do not have an epimysium.
Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
14.1K
The Muscular System01:18

The Muscular System

4.8K
The muscular system is essential to the body's overall structure and function, playing a crucial role in movement, stability, and internal processes. It consists of three distinct types of muscle tissue: the skeletal, the smooth, and the cardiac muscles.
4.8K
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

1.3K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
1.3K
Skeletal Muscle Anatomy00:55

Skeletal Muscle Anatomy

89.6K
Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
89.6K
Overview of Skeletal Muscle01:15

Overview of Skeletal Muscle

12.4K
Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. The sarcolemma, the plasma membrane of a skeletal muscle cell, consists of a lipid bilayer and glycocalyx that supports muscle fibers. The sarcolemma extends into the muscle cells to form tubular structures called transverse or T-tubules. Each side of the T-tubules consists of a membrane-bound structure called the sarcoplasmic reticulum,...
12.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disability-related care trajectories in a pluralistic health system: a qualitative study in urban Sierra Leone.

BMC public health·2026
Same author

Independent Head-to-Head Comparison of Commercial Artificial Intelligence Devices for Lung Cancer Detection on Chest Radiographs.

Radiology·2026
Same author

CARMN fusions and PDGFRB mutations highlight key differences among cutaneous tumors with myopericytic differentiation.

The Journal of investigative dermatology·2026
Same author

Effect of Wearable Activity Tracker Social Behaviors on Physical Activity and Exercise Self-Efficacy: Real-World Pilot Study.

JMIR formative research·2026
Same author

Novel fusion gene THBS1::ERBB2 drives a subset of superficial acral fibromyxomas.

The British journal of dermatology·2026
Same author

A Safe and Effective Internal Medicine Procedure Rotation for Medical Students.

Medical science educator·2026
Same journal

Mammalian Respiratory Chain Complex Assemblies and Their Links to Mitochondria Stress-Induced Human Diseases.

Advances in experimental medicine and biology·2026
Same journal

Enzyme Assemblies in Nucleotide Metabolism: Structure, Regulation, and Disease Implications.

Advances in experimental medicine and biology·2026
Same journal

The Pyruvate Dehydrogenase Complex: A 90-Year-Old Enigma Shaping the Future of Structural Enzymology.

Advances in experimental medicine and biology·2026
Same journal

Regulation of the Anti-termination RNA Transcription Complex by Lon-Mediated Lambda N Degradation.

Advances in experimental medicine and biology·2026
Same journal

PCNA Macromolecular Complexes: PCNA Serves as a Molecular Hub Regulating Multiple Cellular Processes Inside and Outside of the Nucleus.

Advances in experimental medicine and biology·2026
Same journal

Dynamic Assemblies in Genome Maintenance.

Advances in experimental medicine and biology·2026
See all related articles

Related Experiment Video

Updated: Sep 9, 2025

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy
09:04

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy

Published on: February 20, 2018

12.6K

Skeletal Muscle and Cardiovascular Health.

Jonathan Ruiz-Ramie1, Paul G Davis2, Elizabeth Anderson3

  • 1Department of Kinesiology, Augusta University, Augusta, GA, USA.

Advances in Experimental Medicine and Biology
|August 29, 2025
PubMed
Summary
This summary is machine-generated.

Regular exercise and resistance training improve blood lipid levels and liver health. Physical activity is key to managing metabolic syndrome and non-alcoholic fatty liver disease risks.

Keywords:
Atherosclerotic cardiovascular diseaseBlood lipids and LipoproteinsExerciseHypertensionInsulin resistanceMetabolic dyslipidemiaMetabolic syndromeNon-alcoholic fatty liver diseaseNon-alcoholic steatohepatitisPhysical activity

More Related Videos

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

40.7K
Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues
09:30

Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues

Published on: February 18, 2021

4.2K

Related Experiment Videos

Last Updated: Sep 9, 2025

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy
09:04

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy

Published on: February 20, 2018

12.6K
Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique
07:20

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

Published on: September 10, 2014

40.7K
Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues
09:30

Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues

Published on: February 18, 2021

4.2K

Area of Science:

  • Cardiovascular Health
  • Metabolic Disorders
  • Exercise Physiology

Background:

  • Cholesterol and triglycerides (TG) are essential blood lipids crucial for cellular function and energy transport.
  • Elevated blood lipid levels are a significant public health concern in the United States.
  • Metabolic syndrome (MetSyn) and non-alcoholic fatty liver disease (NAFLD) are prevalent conditions linked to lipid metabolism.

Purpose of the Study:

  • To investigate the impact of exercise and physical activity (PA) on blood lipid profiles and metabolic health.
  • To evaluate the role of aerobic exercise and resistance training in managing MetSyn and NAFLD.
  • To understand how exercise influences muscle and liver function in relation to lipid regulation.

Main Methods:

  • Review of existing literature on exercise, physical activity, and their effects on blood lipids, MetSyn, and NAFLD.
  • Analysis of the relationship between different exercise modalities (aerobic vs. resistance) and metabolic health markers.
  • Examination of the physiological mechanisms by which exercise impacts muscle and liver lipid metabolism.

Main Results:

  • Aerobic exercise, particularly at higher intensity ranges, significantly benefits MetSyn factors and improves muscle and liver function.
  • Resistance training demonstrates effectiveness in positively influencing certain MetSyn indicators.
  • Exercise and PA are integral components in the treatment and risk reduction strategies for NAFLD.

Conclusions:

  • Optimizing muscle and liver function through appropriate exercise and PA levels is crucial for reducing the risk of MetSyn and NAFLD.
  • Both aerobic exercise and resistance training play valuable roles in managing metabolic health and preventing associated diseases.
  • Lifestyle modifications, including diet, exercise, and weight management, are foundational for NAFLD treatment and overall metabolic well-being.