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Updated: Jan 16, 2026

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Papillon-Lefèvre Syndrome: Case Report of Two Sisters.

Adnane El-Missioui1, Fatima Zahra Benkarroum1, Hind Ramdi1

  • 1Department of Pediatric Dentistry, Faculty of Dental Medicine, Mohammed V University in Rabat, Morocco.

International Journal of Clinical Pediatric Dentistry
|October 3, 2025
PubMed
Summary

Papillon-Lefèvre syndrome (PLS) is a rare genetic disorder causing severe palmoplantar keratoderma and aggressive periodontitis, leading to early tooth loss. This case report highlights two sisters with PLS, emphasizing diagnosis and management.

Keywords:
Case reportOral featuresPapillon−Lefèvre syndromeSkin lesions

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