Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

844
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
844
Dementia01:30

Dementia

480
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
480
Intellectual Disability01:29

Intellectual Disability

580
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
580
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.5K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.5K
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

281
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
281
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

736
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
736

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Clinical Manifestations.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Basic Science and Pathogenesis.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Polygenic risk for psychiatric disorders and its association with neuropsychiatric symptoms in dementia.

International review of psychiatry (Abingdon, England)·2025
Same author

CSF biomarkers of neuroinflammation are associated with regional atrophy.

Journal of neurology·2025

Related Experiment Video

Updated: Jan 6, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.5K

Dementia: changes from ICD-10 to ICD-11.

Frank Jessen1,2, Karl Broich3

  • 1Department of Psychiatry, Faculty of Medicine, University Hospital Cologne, Kerpener Straße 62, 50937, Cologne, Germany. frank.jessen@uk-koeln.de.

Der Nervenarzt
|October 14, 2025
PubMed
Summary

The International Statistical Classification of Diseases and Related Health Problems version 11 (ICD-11) offers improved dementia classification with severity levels and symptom focus. However, it lacks expert clinical criteria and biomarker integration for neurodegenerative diseases.

Keywords:
Alzheimer’s diseaseBiomarkersMild neurocognitive disorderPostcoordinationSeverity level

More Related Videos

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

18.1K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.9K

Related Experiment Videos

Last Updated: Jan 6, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.5K
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

18.1K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.9K

Area of Science:

  • Neurology
  • Medical Classification Systems

Background:

  • The International Statistical Classification of Diseases and Related Health Problems version 10 (ICD-10) has limitations in classifying dementias.
  • Advancements in understanding neurodegenerative diseases necessitate updated classification systems.

Purpose of the Study:

  • To evaluate the conceptual advances of the International Statistical Classification of Diseases and Related Health Problems version 11 (ICD-11) in dementia classification compared to ICD-10.
  • To identify areas for improvement in ICD-11 regarding the inclusion of clinical criteria and biomarkers for dementia.

Main Methods:

  • Comparative analysis of ICD-11 and ICD-10 classification structures for neurocognitive disorders.
  • Review of the ICD-11 chapter on "Neurocognitive disorders" for coding precision and inclusion of diagnostic features.
  • Assessment of the integration of expert-developed clinical criteria and biomarker information in ICD-11.

Main Results:

  • ICD-11 introduces severity levels and emphasizes mental/behavioral symptoms for more precise dementia coding.
  • A new category for mild neurocognitive disorder as a prodromal dementia state is included in ICD-11.
  • ICD-11 does not sufficiently incorporate expert clinical criteria for specific dementias (e.g., frontotemporal dementia, Lewy body disease) or mention biomarkers for etiological diagnosis.

Conclusions:

  • ICD-11 represents a significant conceptual improvement over ICD-10 for dementia classification.
  • Further updates to ICD-11 are needed to integrate established clinical criteria and biomarker roles in dementia diagnosis.
  • Regular revisions of ICD-11 are crucial given the rapid advancements in neurodegenerative disease research.