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Influence of Climate on Atopic Dermatitis
Kristen Fernandez1, Maya Mundada2, Alexandra So2
1Dermatology Service, San Francisco VA Health Care System, San Francisco, CA, USA; Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Dermatologic Clinics
|November 9, 2025
Summary
Climate change worsens atopic dermatitis (AD) by increasing environmental stressors like pollution and extreme temperatures. Strategies to manage AD risks include patient education and air filtration.
Area of Science:
- Environmental Science
- Dermatology
- Public Health
Background:
- Atopic dermatitis (AD) is a chronic inflammatory skin condition linked to immune issues and skin barrier problems.
- Environmental factors significantly influence AD exacerbation and management.
Purpose of the Study:
- To review recent literature (since April 2023) on the impact of climate change on atopic dermatitis outcomes.
- To identify climate-related triggers and potential mitigation strategies for AD.
Main Methods:
- Literature review focusing on studies published after April 2023.
- Analysis of the relationship between climate variables and AD symptoms.
Main Results:
- Climate change intensifies stressors like temperature extremes, humidity changes, and air pollution.
- These stressors can trigger or worsen AD by increasing oxidative stress, disrupting the skin microbiome, and impairing skin barrier function.
- Current evidence shows suggested associations between climate variables and AD, but findings remain inconsistent.
Conclusions:
- Climate change poses a significant risk for individuals with atopic dermatitis.
- Mitigation strategies include patient education, indoor air filtration, and public health policies to reduce pollution.
- Further research is needed to clarify the inconsistent findings and establish definitive links.
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