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Traditional and Artificial Intelligent Methods in Predicting Maxillofacial Soft Tissue Morphology After Orthognathic
Tianyi Wang1, Huanhuan Chen1, Guangying Song1
1Department of Orthodontics, Cranial-Facial Growth and Development Center, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing 100081, China.
International Journal of Dentistry
|November 10, 2025
Summary
Predicting soft tissue changes after orthognathic surgery is challenging. This review highlights artificial intelligence (AI), particularly deep learning (DL), as a promising method for improving prediction accuracy and speed in surgical planning.
Area of Science:
- Oral and Maxillofacial Surgery
- Medical Imaging
- Artificial Intelligence in Medicine
Background:
- Preoperative prediction of soft tissue morphology after orthognathic surgery remains a significant challenge.
- Traditional 2D prediction methods have limitations in accuracy and scope.
Purpose of the Study:
- To review current prediction methods for soft tissue morphology in orthognathic surgery.
- To evaluate the potential of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in improving prediction accuracy and speed.
- To identify future research directions for enhanced surgical planning.
Main Methods:
- A narrative review of articles was conducted using PubMed.
- Keywords included orthognathic surgery, prediction methods, simulation, AI, ML, DL, soft tissue, and surgical planning.
- Sixty relevant articles were evaluated from an initial search of sixty-seven.
Main Results:
- The transition from 2D to 3D prediction methods has paved the way for AI, especially DL algorithms like DNN, PointNet, and Transformer.
- DL methods demonstrate high accuracy, speed, and ease of use, indicating broad development prospects.
- Key challenges for DL include data insufficiency, overfitting, and lack of interpretability.
Conclusions:
- Deep learning (DL) offers significant potential for improving the accuracy and speed of soft tissue prediction in orthognathic surgery.
- Future improvements can be achieved through large, high-quality databases, specialized datasets, optimized algorithms, multimodal data integration, and visualization techniques.
- Addressing data limitations and interpretability is crucial for the clinical application of DL in surgical planning.

