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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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Tracking the Evolution of Research Topics in Healthcare Informatics Research Using Keywords and MeSH Terms.

Kye Hwa Lee1, Hyejung Chang2

  • 1Department of Information Medicine, Asan Medical Center, Department of Digital Medicine, University of Ulsan College of Medicine, Seoul, Korea.

Healthcare Informatics Research
|November 20, 2025
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Summary
This summary is machine-generated.

This study analyzed Korean health informatics research trends, finding a balance between established topics like electronic health records and emerging areas such as machine learning and telemedicine. The Healthcare Informatics Research journal plays a key role in documenting these evolving priorities.

Keywords:
BibliometricsInformation ManagementMedical InformaticsMedical Subject HeadingsNatural Language Processing

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Area of Science:

  • Health Informatics
  • Medical Informatics
  • Bibliometrics

Background:

  • The field of health informatics is rapidly evolving, driven by technological advancements and changing healthcare needs.
  • Understanding research trends is crucial for identifying emerging priorities and guiding future innovation in medical informatics.
  • The journal Healthcare Informatics Research (HIR) serves as a key platform for documenting Korean health informatics research.

Purpose of the Study:

  • To analyze publication trends and research focus shifts in Healthcare Informatics Research (HIR).
  • To identify evolving priorities and innovations in the Korean medical informatics landscape over time.
  • To examine the interplay between persistent and emerging research themes within the field.

Main Methods:

  • Bibliometric analysis of 958 papers from HIR (1995-2024), focusing on 658 English articles since 2010.
  • Keyword and Medical Subject Headings (MeSH) term analyses (TF-IDF, LDA, co-occurrence) on 632 abstracts.
  • Inferential statistics (chi-square, regression) to assess temporal changes in research trends.

Main Results:

  • Publication trends in HIR showed an increase, peaking between 2015 and 2018.
  • Persistent themes included health systems and electronic health records; emerging topics included machine learning and telemedicine.
  • No statistically significant changes in keyword distribution over time were observed, indicating sustained relevance of core areas.

Conclusions:

  • HIR effectively documents the evolution of Korean health informatics research.
  • The field demonstrates adaptability, balancing foundational healthcare themes with emerging technologies.
  • Future research should broaden scope to other journals and incorporate global perspectives and ethical considerations.