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Updated: Jan 10, 2026

Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions
Published on: November 17, 2021
Glioneuronal Tumors
1Department of Radiology, Phoenix Children's Hospital, Phoenix, AZ, USA; Department of Child Health and Radiology, University of Arizona College of Medicine, AZ, USA; Department of Radiology, Creighton University School of Medicine, AZ, USA.
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Glioneuronal tumors are rare central nervous system neoplasms characterized by mixed neuronal and glial components, predominantly affecting pediatric and young adult populations. This article provides an in-depth analysis of glioneuronal tumors, emphasizing neuroimaging findings critical for diagnosis, differential diagnosis, and surgical planning. MR imaging remains the cornerstone, with advanced techniques like perfusion and functional MR imaging offering additional insights. Prognosis is generally favorable for low-grade tumors, though high-grade variants pose challenges. Innovations in radiomics, molecular profiling, and personalized medicine are transforming management. This article synthesizes current knowledge, highlighting imaging's pivotal role, and future directions.
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