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Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.
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Related Experiment Video

Updated: Jan 13, 2026

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics
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Low-Energy Single-Electron Detector with Submicron Resolution.

Luis Alfredo Ixquiac Méndez1,2, Martino Zanetti1,2, Tilman Kraeft1,2

  • 1University of Vienna, Faculty of Physics, VCQ, 1090 Vienna, Austria.

ACS Photonics
|January 12, 2026
PubMed
Summary
This summary is machine-generated.

Researchers developed a scintillator-based single-electron detector for electron microscopy. This detector achieves high spatial resolution and efficiency, enabling new possibilities for atmospheric electron diffraction studies.

Keywords:
Air-SEMCe scintillatorSingle-electron detectionYAGelectron diffraction at atmospheric pressurehigh-resolution electron detectionlow-energy electron detectorscintillator-based detector

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Area of Science:

  • Physics
  • Materials Science
  • Instrumentation

Background:

  • Single-electron detectors are crucial for electron microscopy and advanced electron optics.
  • Existing detectors face limitations in resolution and applicability for certain experiments.

Purpose of the Study:

  • To develop and characterize a novel scintillator-based single-electron detector.
  • To evaluate its performance in terms of spatial resolution, efficiency, and purity.
  • To explore its potential for enabling atmospheric electron diffraction studies.

Main Methods:

  • Utilized a scintillator material for single-electron detection.
  • Estimated spatial resolution at 0.9 μm for 17 keV electrons.
  • Quantified detection efficiency and purity at 17 keV and 30 keV electron energies.

Main Results:

  • Achieved a spatial resolution of 0.9 μm at 17 keV.
  • Demonstrated detection efficiency and purity greater than 0.8 at 17 keV, reaching 0.96 at 30 keV.
  • Showcased the detector's capability for electron diffraction studies at short sample-detector distances.

Conclusions:

  • The developed scintillator-based detector offers high performance for single-electron detection.
  • Its capabilities potentially open avenues for electron diffraction studies under atmospheric pressure conditions.