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Schulze Ralf1, Spiegl Michael2

  • 1Division of Oral Diagnostic Sciences, School of Dental Medicine, University of Bern.

Swiss Dental Journal
|January 28, 2026
PubMed
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This summary is machine-generated.

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Autologous tooth transplantation using a tooth germ (38) successfully regenerated significant alveolar bone defects. This procedure, combined with orthodontic alignment, demonstrates the osteogenic potential of desmodontal cells for bone regeneration.

Area of Science:

  • Dentistry
  • Oral Surgery
  • Regenerative Medicine

Background:

  • Atypical displacement of mandibular teeth (36 and 37) presents complex clinical challenges.
  • Significant alveolar bone defects can complicate tooth replacement strategies.

Purpose of the Study:

  • To describe a case of autologous tooth transplantation for managing atypical tooth displacement and associated bone defects.
  • To evaluate the osteogenic potential of desmodontal cells in tooth transplantation for alveolar bone regeneration.

Main Methods:

  • Autologous tooth transplantation of a tooth germ (38) into the defect site of tooth 36.
  • Subsequent orthodontic alignment over an 8-month period.
  • Assessment of bone regeneration in the affected alveolar process.
Keywords:
AutologousBone RegenerationMandibleRootsToothTransplantation

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Main Results:

  • Complete regeneration of the pronounced bone defect in the 36/37 region was observed.
  • Successful integration and alignment of the transplanted tooth germ.
  • Significant regeneration of the alveolar process was achieved through the combined approach.

Conclusions:

  • Autologous tooth transplantation is a viable option for managing complex dental anomalies.
  • Desmodontal cells possess significant osteogenic potential, facilitating alveolar bone regeneration.
  • Orthodontic fine adjustment following transplantation enhances functional and aesthetic outcomes and promotes bone regeneration.