This case report describes an autologous tooth transplantation from tooth 38 to tooth 36 associated with atypical displacement of teeth 36 and 37. It demonstrates the osteogenic potential of desmodontal cells in tooth transplantation. The pronounced bone defect in region 36/37 after removal of 36 and the cranially located 37 was completely filled by transplantation of the tooth germ 38 in combination with subsequent orthodontic alignment over the course of 8 months through complete regeneration of the alveolar process. The case shows that tooth autotransplantation and subsequent orthodontic fine adjustment can result in significant regeneration of locally missing alveolar bone.