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A Multi-Band Low-Supply-Voltage 16-QAM Transmitter Based on a Digital Fractional-N PLL With TDC Calibration for
IEEE Transactions on Biomedical Circuits and Systems
|February 16, 2026
Summary
This study introduces a high-data-rate, energy-efficient digital transmitter for capsule endoscopy using 16-QAM modulation. It achieves excellent error vector magnitude (EVM) and power efficiency for wireless medical applications.
Area of Science:
- Electrical Engineering
- Biomedical Engineering
- Wireless Communication
Background:
- Capsule endoscopy requires high data rates and energy efficiency for wireless data transmission.
- Limited battery capacity in capsules necessitates power-efficient transmitter designs.
- Meeting receiver sensitivity specifications demands adequate output power and low noise.
Purpose of the Study:
- To present a highly digital transmitter for multi-band 16-QAM modulation for capsule endoscopy.
- To achieve high data rates with high energy efficiency and output power.
- To reduce power consumption in battery-powered endoscopy capsules.
Main Methods:
- Utilized a counter-assisted digital phase-locked loop (CDPLL) for low-noise clock generation across multiple bands.
- Implemented a time-to-digital converter (TDC) calibration for improved EVM performance.
- Developed a digital power amplifier with high power efficiency.
Main Results:
- The transmitter, fabricated in a 180-nm CMOS process, supports 40 Mbps with 16-QAM modulation.
- Achieved energy efficiency of 0.27/0.26 nJ/bit at 40 MHz data rate and 1.1-V supply.
- Measured EVM of 3.24/3.7% with -5-dBm output power in narrow bandwidths (10 MHz) at 435/415 MHz.
- Reported a figure of merit of 0.86/0.82 nJ/bit/mW in respective bands.
Conclusions:
- The developed digital transmitter meets the stringent requirements for capsule endoscopy, including high data rate, energy efficiency, and output power.
- The CDPLL with TDC calibration significantly improves EVM performance.
- The high-efficiency digital power amplifier contributes to reduced overall system power consumption, extending capsule operation time.

