Investigation of a Mobile, Digital Application to Objectively Assess Cognitive Function in Cancer Survivors

To demonstrate feasibility of the MindCap mobile, digital application for objective and repeated assessment of cognitive function in cancer survivors and assess its sensitivity to cognitive improvement.

57 adults with stage I-III solid tumors or lymphoma who reported cognitive issues six months to five years postchemotherapy.

Participants completed three phases of MindCap testing sessions over 14 weeks. Pre-/postintervention data were collected for time and number of MindCap sessions completed for each phase, adherence to required testing frequency, participant satisfaction, self-report, and MindCap metrics for cognitive domain-specific performance (executive function, attention, memory, verbal ability, visual-spatial ability, and psychomotor function).

Feasibility was demonstrated for recruitment and adherence to MindCap use. Self-report and MindCap metrics correlated positively. MindCap performance metrics were sensitive to improvements in multiple cognitive domains. Post facto analyses indicated a potential MindCap dose effect for cognitive function improvement.

Future research comparing MindCap metrics to standard neurocognitive testing and investigation for potential dose effect are warranted.