Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Apr 14, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
05:30

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

30.0K

Decompressive Craniectomy: Trial Evidence and Impact on Guidelines.

Conor S Gillespie1, Midhun Mohan2, Angelos Kolias3

  • 1Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK; Department of Neurosurgery, Addenbrooke's Hospital, Cambridge, UK.

Neurosurgery Clinics of North America
|April 12, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postoperative outcomes in CNS WHO grade 2 and 3 meningioma: a systematic review and meta-analysis.

Langenbeck's archives of surgery·2026
Same author

DUST: A framework for quantifying dugong-seagrass interactions using low-cost UAVs.

Marine environmental research·2026
Same author

Outlining the global variation in resources for traumatic brain injury care: site-level data from the Global Neurotrauma Outcomes Study (GNOS).

BMJ global health·2026
Same author

A Narrative Review on Neurorehabilitation in India: Current Scenario, Unmet Needs, and the Road to the Future.

Cureus·2026
Same author

Rapid versus gradual weaning of external ventricular drains in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis.

Journal of neurosurgical sciences·2026
Same author

Unanticipated Testicular Involvement in Prostate Carcinoma: A Case Report.

Cureus·2026

Decompressive craniectomy improves survival for traumatic brain injury, stroke, and hemorrhage. Appropriate use of this neurosurgical procedure is now indicated across these conditions based on recent evidence.

Area of Science:

  • Neurosurgery
  • Critical Care Medicine
  • Neurology

Background:

  • Decompressive craniectomy is a neurosurgical procedure debated for traumatic brain injury (TBI), ischemic stroke, and intracerebral hemorrhage.
  • Initial studies suggested increased survival but also potential for higher morbidity.

Purpose of the Study:

  • To review key clinical trials on decompressive craniectomy.
  • To analyze the influence of trial findings on international treatment guidelines.

Main Methods:

  • Review of pivotal randomized controlled trials and retrospective series.
  • Analysis of subsequent updates to international clinical practice guidelines.

Main Results:

  • Emerging evidence from new trials supports the indication of decompressive craniectomy.
Keywords:
DCDecompressive craniectomyICHIntracerebral hemorrhageStrokeTBITraumatic brain injury

More Related Videos

A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation
06:50

A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation

Published on: June 10, 2020

2.4K
Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line
04:06

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

4.0K

Related Experiment Videos

Last Updated: Apr 14, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
05:30

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

30.0K
A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation
06:50

A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation

Published on: June 10, 2020

2.4K
Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line
04:06

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

4.0K
  • Appropriate application of the procedure is crucial for favorable outcomes in TBI, stroke, and hemorrhage.

    • Conclusions:

    • Decompressive craniectomy is indicated for traumatic brain injury, ischemic stroke, and intracerebral hemorrhage when performed correctly.
    • Published trial data has significantly shaped current international guidelines for neurosurgical interventions.