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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...

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Updated: May 22, 2026

Image Rendering Techniques in Postmortem Computed Tomography: Evaluation of Biological Health and Profile in Stranded Cetaceans
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Image Rendering Techniques in Postmortem Computed Tomography: Evaluation of Biological Health and Profile in Stranded Cetaceans

Published on: September 27, 2020

Quantitative SPECT/CT: Technique and Clinical Applications.

Stijn De Schepper1,2, Tim Van den Wyngaert3,4, Philipp Ritt5

  • 1Department of Nuclear Medicine, Antwerp University Hospital, Edegem, Belgium. stijn.deschepper@uza.be.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|May 21, 2026
PubMed
Summary
This summary is machine-generated.

Advancements in single photon emission computed tomography/computed tomography (SPECT/CT) have significantly improved image quality and diagnostic confidence. The development of quantitative SPECT/CT offers precise tracer quantification, enhancing diagnostic accuracy and treatment monitoring.

Keywords:
Clinical SPECTQuantitative SPECT/CTQuantitative imagingSPECT/CTStandardization and harmonization

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Image Rendering Techniques in Postmortem Computed Tomography: Evaluation of Biological Health and Profile in Stranded Cetaceans
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Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
09:55

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

Published on: October 4, 2024

Area of Science:

  • Nuclear medicine
  • Medical imaging
  • Radiophysics

Background:

  • Single photon emission computed tomography (SPECT) has evolved over 50 years, enhancing image quality and diagnostic confidence.
  • Hybrid SPECT/computed tomography (CT) systems, attenuation correction, and iterative reconstruction have become standard, making SPECT/CT the preferred modality in nuclear medicine.
  • Emerging trends include whole-body SPECT/CT and novel semiconductor detector technologies (cadmium telluride, cadmium zinc telluride) for improved sensitivity and energy resolution.

Purpose of the Study:

  • To review the physical and technical fundamentals of SPECT image formation.
  • To outline the prerequisites for quantitative SPECT/CT.
  • To present achievable quantitative accuracy and clinical applications of quantitative SPECT/CT.

Main Methods:

  • Review of physical and technical principles of SPECT imaging.
  • Analysis of requirements for quantitative SPECT/CT.
  • Literature-based assessment of quantitative accuracy.
  • Compilation of clinical use cases.

Main Results:

  • SPECT/CT systems are now the workhorse in nuclear medicine due to technological advancements.
  • Quantitative SPECT/CT enables precise tracer quantification (Bq/mL, SUV), akin to PET.
  • Quantitative SPECT/CT is crucial for longitudinal studies and treatment response monitoring, improving diagnostic accuracy.

Conclusions:

  • Quantitative SPECT/CT represents a major advancement in nuclear medicine imaging.
  • It enhances diagnostic accuracy and confidence, particularly for tracking disease progression and treatment efficacy.
  • The review covers fundamental principles, quantitative prerequisites, accuracy benchmarks, and clinical applications.