Colorectal Cancer Survival: A single-Centre Experience

Area of Science:

• Oncology
• Public Health

Background:

• Colorectal cancer (CRC) is a prevalent malignancy in the UK.
• Survival rates for CRC patients can differ significantly across healthcare centers.
• District hospitals play a crucial role in managing CRC patient outcomes.

Purpose of the Study:

• To report 5-year survival rates for colorectal cancer patients treated at a district hospital.
• To investigate the impact of various patient and treatment-related factors on CRC survival.
• To compare local CRC survival data with national benchmarks.

Main Methods:

• Retrospective review of 405 colorectal cancer patients who received curative treatment between 2017-2019.
• Kaplan-Meier method used to analyze survival rates.
• Cox regression models employed to assess the relationship between survival time and influencing variables.

Main Results:

• Overall 5-year survival rate was 59.3% (2-year survival: 78.5%).
• Five-year survival rates by stage: Stage I (80.9%), Stage II (67.3%), Stage III (55%), Stage IV (10.9%).
• Lower survival rates were observed in male patients, those with colon cancer, patients over 50, those without curative resection, and those receiving adjuvant therapy.

Conclusions:

• The district hospital's CRC survival rates are comparable to other centers, considering local population demographics.
• Patient age, tumor location, gender, curative resection status, and adjuvant therapy significantly affect colorectal cancer survival.
• These findings highlight the importance of personalized treatment strategies and further research into disparities in CRC outcomes.