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Updated: Aug 5, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
Melatonin Amplitude, but Not Phase, Is Associated with Sleep Efficiency in the Arctic
D G Gubin1,2, S N Kolomeychuk3,4, I M Petrov3
1Tyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia. dgubin@mail.ru.
None:
This study investigated the relationship between the amplitude and phase of melatonin rhythm and sleep efficiency in 15 Arctic residents, accounting for the pronounced seasonal variations in the photic environment. Sleep efficiency was assessed using actigraphy across the winter and summer solstices, and the spring equinox. Analysis revealed no significant seasonal variations in sleep efficiency (p > 0.05). Multiple regression analysis, after adjusting for photoperiod, demonstrated a significant positive association between the melatonin amplitude and sleep efficiency (β = 0.317, p < 0.037, η2 = 0.10). Melatonin phase parameters (acrophase or dim light melatonin onset (DLMO)) had no significant relationship with sleep efficiency (p > 0.3). These findings suggest that melatonin amplitude plays a dominant role in determining sleep quality, and substantiate the potential efficacy of interventions aimed at augmenting melatonin rhythm amplitude.
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