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Updated: Aug 16, 2026

Evaluation of Amino Acid Consumption in Cultured Bone Cells and Isolated Bone Shafts
Published on: April 13, 2022
Mild elevations of plasma ornithine in homocystinuria
Abstract:
Hyperornithinemia was found on many occasions during monitoring of amino acids in the fasting plasma of homocystinuric patients. Ornithine concentrations were elevated 2- to 3-fold above the normal mean value. Hyperornithinemia was of much less marked degree than that seen in gyrate atrophy of the choroid and retina, and was not accompanied by overflow ornithinuria or hypolysinemia. Elevations in plasma ornithine concentrations in homocystinuric patients were generally proportional to elevations in the plasma concentration of homocystine, but not that of methionine.
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