Reassessment for reference values for total nucleated cell count and myeloid/erythroid ratio of human bone marrow...

Total uncleated cell count and Myeloid/Erythroid (M/E) ratio of bone marrow aspirate in Japanese was determined in 1962 and no reassessment has been done until now. Therefore, the reassessment work has been performed using our laboratory data. Criterias for healthy individuals were settled and data obtained were applied first for probability plot analysis chart and data which gave asymmetry for the distribution curve were expelled. Then the data sets were processed with Hoffman's 3 time cutting method. As a result, reference values of the count and the ratio were obtained in total and by gender and age. The former values were lower than those reported by previous papers, but the latter values were similar to those reported previously. On the other hand, our manual counting method was compared with the electronic counting method, and good correlation was observed between the both. From the results we concluded that our reference values were acceptable and useful for routine use.