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Persistent altered mentation due to ethanol

M Victor1

  • 1Department of Medicine (Neurology), Dartmouth Medical School, Hanover, New Hampshire.

Neurologic Clinics
|August 1, 1993
PubMed
Summary
This summary is machine-generated.

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Chronic alcohol abuse can harm intellect, personality, and behavior. This article details conditions like Wernicke-Korsakoff syndrome and alcoholic dementia linked to long-term alcohol misuse.

Area of Science:

  • Neurology
  • Toxicology

Background:

  • Chronic alcohol abuse is known to cause cognitive and behavioral decline.
  • Several specific neurological disorders are associated with long-term excessive alcohol consumption.

Purpose of the Study:

  • To discuss the relationship between chronic alcoholism and various dementing diseases.
  • To provide an overview of established mechanisms linking alcohol abuse to neurological deterioration.

Main Methods:

  • Literature review of established neurological conditions associated with alcoholism.
  • Discussion of the pathogenesis and clinical manifestations of alcohol-related brain diseases.

Main Results:

  • Wernicke-Korsakoff syndrome, pellagra, hepatocerebral degeneration, Marchiafava-Bignami disease, and alcoholic dementia are linked to chronic alcohol abuse.

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  • These conditions represent distinct pathways through which alcohol damages the brain, affecting intellect, personality, and behavior.

    • Conclusions:

    • Chronic alcohol abuse is a significant risk factor for developing severe neurological and cognitive impairments.
    • Understanding these alcohol-related dementias is crucial for diagnosis and management in affected individuals.