Related Experiment Videos
Neuronal migrational disorders: diffuse cortical dysplasia or the "double cortex" syndrome
P Iannetti1, U Raucci, L A Basile
1Department of Paediatrics, University La Sapienza, Roma, Italy.
Acta Paediatrica (Oslo, Norway : 1992)
|May 1, 1993
Summary
A 10-year-old girl experienced a seizure due to diffuse cortical dysplasia, also known as double cortex. This rare condition involves abnormal gray matter development in the brain, leading to neurological abnormalities.
Area of Science:
- Neuroscience
- Radiology
- Pediatric Neurology
Background:
- Epilepsy in children requires accurate diagnosis.
- Partial complex seizures can indicate underlying brain abnormalities.
Observation:
- A 10-year-old girl presented with a single partial complex seizure.
- Neurological and psychological evaluations were normal.
- EEG revealed left temporo-occipital abnormalities.
Findings:
- MRI showed bilateral gray matter bands (band heterotopia/double cortex) between ventricles and cortex.
- Enlarged left lateral ventricle and left cortical hemiatrophy were observed.
- Diagnosis of diffuse cortical dysplasia confirmed.
Implications:
- This case highlights the importance of advanced neuroimaging in diagnosing rare cortical malformations.
- Understanding band heterotopia is crucial for managing pediatric epilepsy.
- Cortical development abnormalities can present with varied neurological symptoms.