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G proteins and endothelium-dependent relaxations

C M Boulanger1, P M Vanhoutte

  • 1INSERM, Hôpital Lariboisière, Paris, France. cboulang@infobiogen.fr

Journal of Vascular Research
|May 1, 1997
PubMed
Summary

Pertussis toxin reveals that G(i) proteins are crucial for nitric oxide (NO) release in endothelial cells. Impaired G(i) function in regenerated endothelium may lead to vasospasm and atherosclerosis.

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