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[The expression of Bordetella pertussis protective antigens during bacterial multiplication on a medium with a fixed
Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|March 1, 1997
Abstract:
The possibility of obtaining native pertussis preparations with high immunobiological activity has been shown. To obtain such preparations, the use of B. pertussis selected strain, its growth under the conditions of static cultivation in a synthetic culture medium and the use of supernatants with the maximum content of protective antigens with the aim of obtaining protective complexes are necessary.