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Recurrent nodular scleritis associated with varicella zoster virus
C Livir-Rallatos1, Y El-Shabrawi, P Zatirakis
1Uveitis and Immunology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
American Journal of Ophthalmology
|October 21, 1998
Summary
Recurrent nodular scleritis can be caused by varicella zoster virus reactivation. This case highlights the importance of considering viral causes in patients with recurrent eye inflammation.
Area of Science:
- Ophthalmology
- Virology
- Immunology
Background:
- Recurrent nodular scleritis is an inflammatory eye condition.
- Varicella zoster virus (VZV) is a common human herpesvirus.
Observation:
- A patient with a history of recurrent nodular scleritis presented with inflamed sclera.
- Biopsy of the inflamed sclera was performed.
Findings:
- Immunohistochemistry and PCR detected VZV antigen and DNA in the scleral biopsy.
- This suggests VZV reactivation as the cause of scleritis.
Implications:
- VZV reactivation should be considered in cases of recurrent nodular scleritis.
- Ophthalmologists should be aware of the potential link between VZV and scleritis.
- Further research may explore antiviral therapies for VZV-related scleritis.