Hannah L Woodward

8PUBLICATIONS
16CO-AUTHORS
Molecular targetsCheminformatics and quantitative structure-activity relationshipsProteins and peptidesBiologically active molecules
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Publications (8)

|Jun 22, 2022
Structural Analysis and Development of Notum Fragment Screening Hits.

Yuguang Zhao, William Mahy, Nicky J Willis

|May 10, 2022
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.

Nicky J Willis, William Mahy, James Sipthorp

|Mar 30, 2021
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling.

Elliott D Bayle, Fredrik Svensson, Benjamin N Atkinson

|Oct 30, 2020
5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit.

William Mahy, Nicky J Willis, Yuguang Zhao

|Aug 14, 2020
Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity.

William Mahy, Mikesh Patel, David Steadman

|Apr 11, 2020
Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders.

Benjamin R Bellenie, Kwai-Ming J Cheung, Ana Varela

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Frequent Collaborators

6 joint publications

Paul V Fish

4 joint publications

Benjamin N Atkinson

4 joint publications

Yuguang Zhao

4 joint publications

Fredrik Svensson