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Primary adrenal lymphoma with choroidal metastases
Lisa S Schocket1, Nasreen A Syed, Stuart L Fine
1Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. lschocket@yahoo.com
American Journal of Ophthalmology
|November 14, 2002
Summary
This case report details a rare instance of bilateral primary adrenal lymphoma that spread exclusively to the eye. The patient achieved complete remission with chemotherapy, showing no recurrence for seven years.
Area of Science:
- Ophthalmology
- Oncology
- Endocrinology
Background:
- Bilateral primary adrenal lymphoma is an exceptionally rare condition.
- Metastases from adrenal lymphoma typically involve lymph nodes, liver, or lungs, rarely presenting solely in the eye.
Observation:
- A 71-year-old male presented with diminished visual acuity in his left eye.
- Ophthalmic examination revealed an exudative retinal detachment.
- Abdominal CT and biopsy confirmed non-Hodgkin large-cell lymphoma affecting both adrenal glands.
Findings:
- The patient received six cycles of chemotherapy (cytoxan, adriamycin, vincristine, prednisone).
- Both ocular and adrenal lesions demonstrated complete resolution post-treatment.
- The patient remained disease-free for seven years, with no recurrence of ocular or systemic lymphoma.
Implications:
- This case highlights the possibility of exclusive ocular metastasis from bilateral primary adrenal lymphoma.
- It underscores the importance of thorough ophthalmic evaluation in patients diagnosed with adrenal lymphoma.
- Successful management with chemotherapy suggests a favorable prognosis for this rare presentation.