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Updated: Aug 15, 2026

Human T Lymphocyte Isolation, Culture and Analysis of Migration In Vitro
Published on: June 2, 2010
[Electrophoretic lymphocyte motility in tonsils of patients with chronic tonsillitis]
1A.A. Bogomoletz National Medical University, Kiev.
Abstract:
The changes in the electrophoresis motility (EPM) of lymphocytes in the tonsils of patients with chronic tonsillitis were assessed using the method of microelectrophoresis. Tonsil lymphocytes of healthy volunteers were used as controls of these experiments. During this investigation it was shown that the average value of EPM of lymphocytes in the control group was -0.98 +/- 0.02 mumol.cm.V-1.S-1. The absolute value of TPM of lymphocytes of the patients with chronic tonssillitis in average dropped 16% to a value of -0.82 +/- 0.02 mumol.cm.V-1.S-1. The percent composition of lymphocytes, whose EPM was close to 0, is higher in the group of patients with chronic tonsillitis, then in the control group. Mathematical analysis were conducted on the experimental data and on the basis of the results it was proposed that the drop of the absolute value of EPM during chronic tonsillitis is connected with the drop in the amount of active lymphocytes.

