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Updated: Aug 11, 2026

MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges
Published on: December 17, 2014
[Assessment of the cerebrovascular reserve in humans]
Abstract:
A new approach of assessment of cerebrovascular reserve in healthy human is proposed. Twenty-two healthy men volunteers aged 25-43 were examined. Investigation of cerebral blood circulation in each of them was implemented for the six times with one-week interval. The cerebral blood flow was measured by use of Doppler ultrasound. Blood flow velocity in the middle cerebral artery and homolateral internal jugular vein and pulsative index in this artery were considered as basic structural elements of cerebral blood circulation in this work. Breath-holding, hyperventilation and stress tests served as functional tests. It was shown that degree of basic parameters synchronization in a system cerebral blood circulation under the influence of functional load determine his cerebrovascular reserve. This method of cerebrovascular reserve estimation could be used for determination of psychophysical readiness of separate human to professional occupation.
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