Objective accommodative amplitude and dynamics with the 1CU accommodative intraocular lens.

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Optics

Background:

• The development of accommodating intraocular lenses (IOLs) aims to restore the natural focusing ability of the eye after cataract surgery.
• The one-compartment-unit (1CU) IOL is designed to provide accommodative function.
• Evaluating the objective and subjective accommodative performance of IOLs is crucial for understanding their clinical efficacy.

Purpose of the Study:

• To compare the objective accommodative amplitude and dynamics of the 1CU accommodative IOL with subjective measurements.
• To assess the long-term changes in accommodation after 1CU IOL implantation.

Main Methods:

• Twenty eyes with 1CU IOLs were evaluated using autorefractors (SRW-5000, PowerRefractor) for static and dynamic accommodation measurements.
• Visual acuity was assessed using logMAR charts, and wavefront aberrometry was performed.
• Subjective amplitude of accommodation was measured using the Royal Air Force (RAF) rule.

Main Results:

• Objective static and dynamic accommodation amplitudes were limited (0.72 D and 0.71 D, respectively) with a noticeable lag.
• Subjective amplitude of accommodation was significantly higher (2.24 D), potentially due to depth of focus.
• By the 2-year follow-up, near visual acuity and both subjective and objective accommodation amplitudes showed a decrease.

Conclusions:

• The 1CU IOL exhibits limited objective accommodative capabilities.
• Patient's subjective accommodation may be enhanced by the IOL's aspheric design and the eye's depth of focus.
• A decline in accommodative function was observed over the 2-year period post-implantation.