Related Experiment Video
Updated: Jul 8, 2026
14:15
Multicolor 3D Printing of Complex Intracranial Tumors in Neurosurgery
Published on: January 11, 2020
Chondroma/Chondrosarcoma of the spine
Gregory S McLoughlin1, Daniel M Sciubba, Jean-Paul Wolinsky
1Division of Neurosurgery, University of Saskatchewan, University Hospital, 103 Hospital Drive, Saskatoon, Saskatchewan, S7N 0W8, Canada.
Neurosurgery Clinics of North America
|December 25, 2007
Summary
Cartilage tumors like chondromas and chondrosarcomas rarely affect the spine. Complete surgical removal is key for treating these tumors, especially malignant chondrosarcomas, as they resist standard therapies.
Area of Science:
- Orthopedic Oncology
- Spinal Neoplasms
Background:
- Chondromas and chondrosarcomas are rare cartilage-forming tumors of the spine.
- These neoplasms represent a spectrum from benign (chondroma) to malignant (chondrosarcoma).
- Tumor grade significantly impacts patient prognosis, distinguishing them from other sarcomas.
Purpose of the Study:
- To review the characteristics and management of spinal chondromas and chondrosarcomas.
- To emphasize the importance of surgical resection for these rare spinal tumors.
Main Methods:
- Literature review on spinal chondromas and chondrosarcomas.
- Analysis of treatment modalities, including surgery, chemotherapy, and radiation therapy.
Main Results:
- Complete en bloc resection is the preferred surgical approach for chondrosarcomas.
- Surgical management can lead to prolonged survival for patients with chondrosarcomas.
- Spinal chondromas and chondrosarcomas demonstrate resistance to conventional chemotherapy and radiation.
Conclusions:
- Optimal management for spinal chondrosarcomas involves complete surgical resection.
- Hypofractionated stereotactic radiation therapy may offer a potential, albeit uncertain, role in slowing tumor progression.
Related Concept Videos
01:27Growth of Cartilage and Bone Tissue
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
01:03Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
01:29Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...