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Forward-imaging instruments for optical coherence tomography.

S A Boppart, B E Bouma, C Pitris

    Optics Letters
    |January 12, 2008
    PubMed
    Summary
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    New surgical probes enable forward-imaging optical coherence tomography (OCT) for subsurface tissue visualization. This technology aids surgeons by providing real-time cross-sectional and enface views during procedures.

    Area of Science:

    • Biomedical Optics
    • Surgical Imaging Technologies
    • Medical Device Engineering

    Background:

    • Optical coherence tomography (OCT) is a valuable non-invasive imaging modality.
    • Existing OCT systems often lack forward-imaging capabilities crucial for surgical guidance.
    • Need for advanced OCT instrumentation for real-time subsurface tissue assessment in surgery.

    Purpose of the Study:

    • To design and implement novel forward-imaging instruments for surgical OCT.
    • To develop a hand-held probe for open surgery and a rigid laparoscope for minimally invasive surgery.
    • To demonstrate the utility of these OCT systems for in vitro human tissue imaging.

    Main Methods:

    • Design and construction of single-spatial-mode optical radiation delivery and collection systems.

    Related Experiment Videos

  • Integration of scanning mechanisms for OCT data acquisition.
  • Development of a hand-held probe for open surgery and a rigid laparoscope for minimally invasive procedures.

    • Main Results:

    • Successful implementation of forward-imaging OCT instruments.
    • Demonstration of a hand-held probe providing cross-sectional subsurface tissue images prior to incision.
    • Validation of a rigid laparoscope enabling simultaneous enface and cross-sectional OCT imaging during minimally invasive procedures.

    Conclusions:

    • Forward-imaging OCT probes offer significant potential for surgical guidance and tissue characterization.
    • The developed instruments are suitable for both open and minimally invasive surgical applications.
    • OCT imaging of in vitro human specimens confirms the feasibility and effectiveness of the proposed technology.