Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

Overview
Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
Transgenic Organisms00:53

Transgenic Organisms

Overview
Transgenic Organisms00:53

Transgenic Organisms

Overview
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Psychogenic disorders and sexual dysfunctions in women with infertility].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[Menopausal hormone therapy in patients with cardiovascular and metabolic diseases: an interdisciplinary Delphi consensus among Russian gynecologists, cardiologists, endocrinologists, gerontologists and geriatricians, phlebologists, and clinical pharmacologists].

Terapevticheskii arkhiv·2026
Same author

[Russian eligibility criteria for prescription of menopausal hormone therapy to patients with cardiovascular and metabolic diseases. Agreement document of RKO, ROAG, RAE, EAT, AFR, RNMOT, RAGG].

Problemy endokrinologii·2026
Same author

[Russian Eligibility Criteria for Prescribing Menopausal Hormone Therapy to Patients With Cardiovascular and Metabolic Diseases. Consensus Document of RSC, RSOG, RAE, EUAT, RAP, RSMSI, RAGG].

Kardiologiia·2025
Same author

Immunohistochemical Expression of GFAP in the Brain Astrocytes of Deceased Newborns Depending on the Postmortem Interval.

Bulletin of experimental biology and medicine·2024
Same author

Morphometric Characteristics of Postmortem Changes in the Brain of Newborns Depending on the Duration of the Postmortem Period.

Bulletin of experimental biology and medicine·2024
Same journal

THE PECULIARITIES OF ARGINASE PATHWAY OF L-ARGININE IN SPERMATOZOA IN MEN WITH DIFFERENT FORMS OF PATHOSPERMIA.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)·2018
Same journal

THE EFFECT OF GADOLINIUM ORTHOVANADATE NANOPARTICLES BY NEONATAL INDUCED REPRODUCTIVE DISEASE IN MALE RATS.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)·2018
Same journal

STATUS OF GLUTATHIONE-DEPENDENT LINK OF BLOOD ANTIOXIDANT SYSTEM UNDER APPLICATION OF FENUGREEK SEED POWDER IN ANIMALS WITH EXPERIMENTAL OBESITY.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)·2018
Same journal

COMPARISON OF SPECTROSCOPIC PROPERTIES OF INTRAOCULAR FLUID IN PATIENTS WITH CATARACT AND PRIMARY OPEN-ANGLE GLAUCOMA.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)·2018
Same journal

EFFECT OF HYDROGEN SULPHIDE DONOR ON INTRAOCULAR PRESSURE IN RATS.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)·2018
Same journal

Flavonoid quercetin reduces gliosis after repetitive mild traumatic brain injury in mice.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)·2018
See all related articles

Related Experiment Video

Updated: Jul 2, 2026

Transfecting and Nucleofecting Human Induced Pluripotent Stem Cells
10:24

Transfecting and Nucleofecting Human Induced Pluripotent Stem Cells

Published on: October 5, 2011

[Gene-engineering technologies and stem cells].

N Ia Spivak, G T Sukhikh, I M Bogdanova

    Fiziolohichnyi Zhurnal (Kiev, Ukraine : 1994)
    |September 4, 2008
    PubMed
    Summary
    This summary is machine-generated.

    This review analyzes the use of stem cells (SC) in ex vivo gene therapy, detailing vector systems for SC transfection and clinical applications for various diseases. It emphasizes ensuring the biosecurity of these advanced therapeutic approaches.

    More Related Videos

    Mouse Genome Engineering Using Designer Nucleases
    12:04

    Mouse Genome Engineering Using Designer Nucleases

    Published on: April 2, 2014

    Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation
    09:51

    Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation

    Published on: February 2, 2016

    Related Experiment Videos

    Last Updated: Jul 2, 2026

    Transfecting and Nucleofecting Human Induced Pluripotent Stem Cells
    10:24

    Transfecting and Nucleofecting Human Induced Pluripotent Stem Cells

    Published on: October 5, 2011

    Mouse Genome Engineering Using Designer Nucleases
    12:04

    Mouse Genome Engineering Using Designer Nucleases

    Published on: April 2, 2014

    Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation
    09:51

    Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation

    Published on: February 2, 2016

    Area of Science:

    • Biotechnology
    • Molecular Biology
    • Regenerative Medicine

    Context:

    • Examines the current landscape of stem cell applications in gene therapy.
    • Focuses on ex vivo gene modification techniques for stem cells.

    Purpose:

    • To provide a conceptual analysis of stem cell use in gene therapy.
    • To expound principles of vector systems for stem cell transfection.
    • To review experimental and clinical data on genetically modified stem cell transplantation.

    Summary:

    • Discusses the construction of vector systems for efficient stem cell transfection.
    • Presents findings from experimental studies and clinical trials involving genetically modified stem cells.
    • Highlights the critical aspect of biosecurity in stem cell-based gene therapy.

    Impact:

    • Informs the development of novel gene therapy strategies using stem cells.
    • Addresses challenges and solutions for safe and effective stem cell transplantation.
    • Contributes to the advancement of treatments for monogenous and multifactorial diseases.