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Improved SNR efficiency in gradient echo coronary MRA with high temporal resolution using parallel imaging.

Jing Yu1, Michael Schär, Evert-Jan Vonken

  • 1Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

Magnetic Resonance in Medicine
|September 26, 2009
PubMed
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Sensitivity encoding (SENSE) enhances signal-to-noise ratio (SNR) in coronary magnetic resonance angiography. This technique improves SNR by optimizing radiofrequency excitations and readout bandwidth, achieving up to 55% enhancement in vivo.

Area of Science:

  • Cardiovascular Imaging
  • Magnetic Resonance Imaging
  • Biomedical Engineering

Background:

  • Coronary magnetic resonance angiography (MRA) techniques face limitations due to signal-to-noise ratio (SNR) constraints.
  • Existing coronary MRA methods struggle to balance temporal and spatial resolution with adequate image quality.

Purpose of the Study:

  • To investigate the application of sensitivity encoding (SENSE) for enhancing SNR in gradient echo coronary MRA.
  • To evaluate the feasibility of SENSE in improving SNR by optimizing radiofrequency (RF) duty cycle in coronary MRA.

Main Methods:

  • Numerical simulations were performed to model the SNR enhancement using SENSE.
  • In vitro and in vivo studies were conducted to validate the proposed SENSE technique for coronary MRA.

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  • The method involves reducing RF excitations and signal readout bandwidth to improve the RF receive to RF transmit duty cycle.

    • Main Results:

    • A maximum SNR enhancement of 55% was achieved for coronary MRA in both in vitro and in vivo experiments.
    • The experimental results demonstrated strong consistency with the numerical simulations.
    • The proposed SENSE method is particularly suitable for spoiled gradient echo coronary MRA requiring high temporal and spatial resolution.

    Conclusions:

    • Sensitivity encoding (SENSE) effectively enhances SNR in coronary MRA, overcoming existing limitations.
    • The SENSE technique offers a viable approach to improve image quality in high-resolution coronary MRA.
    • This method holds promise for advancing diagnostic capabilities in cardiovascular magnetic resonance imaging.