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Updated: Jun 1, 2026
Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
Published on: October 14, 2016
Collateral blood flow can predict myocardial blush grade in primary coronary intervention
Reuben Ilia1, Arik Wolak, Guy Amit
1Cardiology Department, Soroka Medical Center and Ben-Gurion University of the Negev, Beer-Sheva, Israel. iliar@bgu.ac.il
Objectives:
Our aim was to investigate whether collateral flow may predict myocardial blush grade (MBG) in acute myocardial infarction patients undergoing primary percutaneous coronary intervention.
Background:
No-reflow is a well known phenomenon associated with increased morbidity and mortality due to underperfused myocardium; therefore early prediction of no-reflow is of major importance. We have observed that in patients with good collateral filling of the infarct related artery as seen prior to primary angioplasty, the clearance of the contrast medium from the myocardium may be impaired.
Methods:
We retrospectively analyzed the MBG as observed by collateral filling in 81 patients and correlated it with the final MBG. Patients were divided into two groups-those with collateral MBG 0 or 1 (34) and those with myocardial blush 2 or 3 (47).
Results:
Of the 34 patients in the first group 71% remained in the same MBG group after primary percutaneous coronary intervention and the rest improved. Of the 47 individuals with collateral MBG 2 or 3, 87% remained in the same group following primary percutaneous coronary intervention, and the rest deteriorated (P < 0.01 for both groups).
Conclusions:
Collaterals may predict MBG in acute myocardial infarction patients undergoing primary percutaneous coronary intervention.
