Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

2.3K
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
2.3K
Microbial Biosensors01:17

Microbial Biosensors

88
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
88
Amperometry: Overview01:10

Amperometry: Overview

2.2K
Amperometry is a technique commonly used to measure the concentration of specific analytes in a solution by monitoring the electric current generated during an electrochemical reaction. It involves applying a constant potential between a working electrode and a reference electrode to measure the resulting current, which is proportional to the concentration of the analyte. The Clark oxygen electrode operates based on this principle of amperometry. It consists of a cathode and an anode enclosed...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vitamin D Deficiency and Markers of Liver Disease in American Indian Adolescents: The Strong Heart Family Study (SHFS).

Biomedicines·2026
Same author

Intelligent soft robotic gripper for non-destructive grasping and attribute recognition via multi-modal waveguide tactile sensors.

Microsystems & nanoengineering·2026
Same author

Personalized non-invasive continuous glucose monitoring via multiparameter-informed machine learning.

Biosensors & bioelectronics·2026
Same author

DEL2PH4: Predictive 3D Pharmacophores from DNA-Encoded Library Screening Data.

ACS medicinal chemistry letters·2026
Same author

Gut microbial IgA coating in infants with traditional farming lifestyle and urban infants with allergic outcomes.

Frontiers in immunology·2026
Same author

Exploring a Single Music Therapy Session to Reduce 22q11.2 Deletion Syndrome Child and Adolescent's Outpatient Clinic-Related Anxiety.

Journal of paediatrics and child health·2026
Same journal

High-Bandwidth AFM Probes for Imaging in Air and Fluid.

Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems·2026
Same journal

Compact, scan-pattern-switchable 2D piezoelectric MEMS mirror with 1D addressable scanning.

Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems·2026
Same journal

Fabrication of LCE Microactuator Arrays Through Soft Lithography with Surface Alignment.

Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems·2025
Same journal

An integrated, optofluidic system with aligned optical waveguides, microlenses, and coupling prisms for fluorescence sensing.

Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems·2024
Same journal

Gold Nanorod-Embedded PDMS Micro-Pillar Array for Localized Photothermal Stimulation.

Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems·2024
Same journal

Fabrication of Out-of-Plane High Channel Density Microelectrode Neural Array with 3D Recording and Stimulation Capabilities.

Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems·2024
See all related articles

Related Experiment Video

Updated: May 3, 2026

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

10.1K

A MEMS Dielectric Affinity Glucose Biosensor.

Xian Huang1, Siqi Li2, Erin Davis2

  • 1Department of Mechanical Engineering, Columbia University, New York, NY 10027 USA.

Journal of Microelectromechanical Systems : a Joint IEEE and ASME Publication on Microstructures, Microactuators, Microsensors, and Microsystems
|February 11, 2014
PubMed
Summary
This summary is machine-generated.

A new implantable biosensor offers reliable, real-time continuous glucose monitoring (CGM) without moving parts. This dielectric affinity sensor shows promise for stable, long-term diabetes management.

Keywords:
Dielectric biosensoraffinity detectioncontinuous glucose monitoringmicroelectromechanical systems technology

More Related Videos

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

13.7K
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
07:51

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection

Published on: February 1, 2022

2.9K

Related Experiment Videos

Last Updated: May 3, 2026

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

10.1K
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

13.7K
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
07:51

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection

Published on: February 1, 2022

2.9K

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Analytical Chemistry

Background:

  • Continuous glucose monitoring (CGM) is crucial for diabetes management.
  • Existing affinity-based CGM sensors often lack reliability due to mechanical complexity.
  • Previous dielectric glucose sensors showed promise but lacked in-vivo capabilities.

Purpose of the Study:

  • To develop a fully implantable MEMS dielectric affinity glucose biosensor.
  • To overcome limitations of previous designs for real-time, subcutaneous monitoring.
  • To create a reliable and stable glucose detection system.

Main Methods:

  • Fabrication of a MEMS-based capacitive biosensor with a perforated electrode and suspended diaphragm.
  • Integration of glucose-sensitive polymers for affinity detection.
  • In-vitro testing with glucose solutions at physiological concentrations.

Main Results:

  • The sensor demonstrated accurate detection of glucose at physiological concentrations.
  • The device exhibited good reversibility and reliability.
  • A time constant of approximately 3 minutes for glucose concentration change was achieved, comparable to commercial systems.

Conclusions:

  • The developed MEMS dielectric affinity glucose biosensor enables real-time, in-vivo monitoring.
  • The sensor's design, free of moving parts, enhances long-term stability and reliability for implantable CGM.
  • This technology holds significant potential for advanced, fully implantable continuous glucose monitoring systems.