Related Experiment Video
Updated: Apr 21, 2026

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure
Published on: June 5, 2020
Characterization of Cr(V)-induced genotoxicity using CdTe nanocrystals as fluorescent probes
Wen-Hao Zhang1, Chao-Xia Sui, Xie Wang
1Henan Provincial Center for Disease Control and Prevention, Henan, Zhengzhou, 450003, People's Republic of China. cdcwhzhang@gmail.com.
Abstract:
CdTe nanocrystals capped by cysteamine were synthesized to study Cr(V)-induced genotoxicity. On the surface of TiO2 thin films, the stepwise process of DNA breakage induced by Cr(V)-GSH complexes was vividly observed by using CdTe-DNA self-assembled fluorescent probes; in acetate buffer solution, an analytical method was developed to detect Cr(V)-induced genotoxicity with CdTe fluorescent probes.
Related Concept Videos
Mutagenicity and Carcinogenicity
Labeling DNA Probes
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

