Related Experiment Videos
[Biological activity of gamma interferon on various cell types in human and murine systems]
M Zucca1, M Fiscella, G Gribaudo
1Istituto di Microbiologia dell'Università di Torino.
Giornale Di Batteriologia, Virologia Ed Immunologia
|January 1, 1989
Abstract:
The effects of interferon (IFN gamma) and of IFN alpha/beta on normal T and B lymphocytes and various T and non-T human and murine cell lines have been investigated. IFN gamma, unlike IFN alpha/beta, did not promote the antiviral state in T cells. The lack of antiviral activity was confirmed at the biochemical level by the finding that 2',5' oligoadenylate synthetase activity is not induced in T cells by IFN gamma only.