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Emerging risk factors for glaucoma onset and progression.
Dana Blumberg1, Alon Skaat2, Jeffrey M Liebmann1
1Bernard and Shirlee Brown Glaucoma Research Laboratory, Edward S. Harkness Eye Institute, Columbia University Medical Center, New York, NY, USA.
Progress in Brain Research
|November 1, 2015
Summary
Glaucoma damages the optic nerve, causing irreversible vision loss. Identifying ocular and systemic risk factors is key for early detection and managing this complex neurodegenerative disease.
Area of Science:
- Ophthalmology
- Neuroscience
- Genetics
Background:
- Glaucoma is a complex, multifactorial neurodegenerative disease.
- It causes progressive optic nerve damage and irreversible visual impairment.
- Identifying ocular and systemic risk factors is critical for disease detection and surveillance.
Purpose of the Study:
- To enhance understanding of glaucoma risk factors.
- To leverage advancements in glaucoma genetics and phenotypes.
- To improve identification of individuals at high risk for visual impairment.
Main Methods:
- Review of current knowledge on glaucoma risk factors.
- Integration of expanding knowledge of glaucoma genotypes and phenotypes.
- Incorporation of technological advancements in disease progression understanding.
Main Results:
- Expanding knowledge of glaucoma genotypes and phenotypes is enhancing risk identification.
- Advancements in technology and disease progression understanding are improving risk assessment.
- A comprehensive understanding of risk factors is crucial for managing glaucoma.
Conclusions:
- Continued research into glaucoma genotypes and phenotypes is vital.
- Technological advancements are crucial for understanding disease progression.
- Improved identification of at-risk individuals will aid in preventing visual impairment.
Keywords:
Beta-zone parapapillary atrophyDisc hemorrhageIntraocular pressureLamina cribrosaRisk factorsMore Related Videos
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