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The TRPCs, Orais and STIMs in ER/PM Junctions.

Dong Min Shin1, Aran Son2, Seonghee Park3

  • 1Department of Oral Biology, BK 21 PLUS Project, Yonsei University College of Dentistry, Seoul, 120-752, South Korea. dmshin@yuhs.ac.

Advances in Experimental Medicine and Biology
|May 11, 2016
PubMed
Summary

Calcium (Ca2+) signaling, crucial for cellular communication, is regulated at ER/PM junctions by STIM proteins interacting with Orai and TRPC channels. This interaction controls Ca2+ influx, impacting cellular responses.

Keywords:
ER/PM junctionOraiSTIM1STIM2TRPC channels

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